Scientists find new gene tool for predicting course of prostate cancer
Researchers from UR Medicine's Wilmot Cancer Institute and Roswell Park Cancer Institute in Buffalo reported in the journal Oncotarget, they have discovered a possible new tool for predicting whether...
View ArticleResearch team identifies role for a microRNA involved in prostate cancer...
Metastasis, or spread of a tumor from the site of origin to additional organs, causes the vast majority of cancer-related deaths, but our understanding of the molecular mechanisms behind metastasis...
View ArticleResearchers identify 'synthetic essentiality' as novel approach for locating...
A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate...
View ArticleNew 'blood biopsies' with experimental device may improve cancer diagnosis...
A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and...
View ArticleLimiting lung cancer's spread and growth in the brain
More people die of lung cancer each year than breast, colon, and prostate cancers combined. One particularly lethal form of the disease is lung adenocarcinoma or LUAD, which afflicts both smokers and...
View ArticleProstate cancer cells grow with malfunction of cholesterol control in cells
Advanced prostate cancer and high blood cholesterol have long been known to be connected, but it has been a chicken-or-egg problem.
View ArticleTargeting of tracked tumor foci ups gleason score upgrading
(HealthDay)—Targeting of tracked tumor foci allows for improved detection of Gleason score 4 + 3 or greater cancers among men under active surveillance for prostate cancer, according to a study...
View ArticleBy boosting innate immunity, researchers eradicate aggressive prostate cancer...
Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors...
View ArticleNovel genes identified that help suppress prostate and other cancers
New genes which help prevent prostate, skin and breast cancer development in mice have been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators. The study...
View ArticleMark of malignancy identified in prostate cancer
Prostate cancer is the second deadliest cancer in men in the U.S. It kills more than 26,000 men in the country every year. But, as in the case of breast cancer, one prostate cancer will progress...
View ArticleAdvanced prostate cancer treatment failure due to cell reprogramming
Columbia University Medical Center (CUMC) researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to...
View ArticleScientists identify biomarkers to guide hormone therapy for prostate cancer
A test commonly used in breast cancer has been found to also identify which patients with aggressive prostate cancer will benefit from hormonal therapy, according to a study led by scientists at UC San...
View ArticleNovel sequencing approach seeks to detect cancer's genomic alterations
Findings from an early study evaluating a sophisticated new genomic-sequencing approach that analyzes cell-free DNA (cfDNA) in the blood of people with advanced cancer will help inform development of a...
View ArticleTargeted photodynamic therapy shown highly effective against prostate cancer
Researchers presenting a preclinical study at the 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) demonstrated the efficacy and optimal dose for targeted...
View ArticleTeam discovers similarities between next-generation prostate cancer drugs
Cleveland Clinic researchers have shown for the first time how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they...
View ArticleGenes may cause tumor aggressiveness and drug resistance in African-American...
A form of genetic variation, called differential RNA splicing, may have a role in tumor aggressiveness and drug resistance in African American men with prostate cancer. Researchers at the George...
View ArticleBlood test predicts prostate tumor resistance
When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that renders them resistant to particular...
View ArticleBlood tumor markers may warn when lung cancer patients are progressing
For many years, oncologists have known that cancers can secrete complex molecules into the blood and that levels of these molecules can be easily measured. These so-called 'tumor markers' are...
View ArticleDouble targeting ligands to identify and treat prostate cancer
Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects. The new approach utilizes a...
View ArticleStudy shows how nerves drive prostate cancer
In a study in today's issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch...
View ArticlePreclinical study in prostate cancer shows that virus-based drug candidate...
One of the most important areas of cancer research today involves efforts to expand the benefits of immunotherapy to more patients. Research conducted by scientists at Roswell Park Cancer Institute in...
View ArticleResearchers identify molecule that helps cancer stay alive, use antibody...
Certain cancer cells stave off their death with help from a particular molecule in a protein involved in the body's immune system response, a research team at Rush University Medical Center has found....
View ArticleNew techniques give blood biopsies greater promise
Researchers at the Broad Institute of MIT and Harvard, Koch Institute at MIT, Dana-Farber Cancer Institute, and Massachusetts General Hospital have developed an accurate, scalable approach for...
View ArticleNano-targeting treatment for prostate cancer
Metastatic or castrate-resistant prostate cancer can spread to the bone in certain patients. While several new treatments are available, they can have a difficult time reaching the bone and can result...
View ArticleCell death linked to tumor growth in prostate cancer patients
The goal of any cancer treatment is to kill tumor cells. Yet, one little understood paradox of certain cancers is that the body's natural process for removing dead and dying cells can actually fuel...
View ArticleResearchers report a new target to treat prostate cancer
The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present...
View ArticleResearch identifies cells that may be responsible for prostate cancer recurrence
Although men with prostate cancer usually respond to standard treatment with hormone therapy or chemotherapy, many will eventually experience progression or recurrence despite treatment—particularly...
View ArticleCancer's gene-determined 'immune landscape' dictates progression of prostate...
The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in...
View ArticleDietary fat, changes in fat metabolism may promote prostate cancer metastasis
Prostate tumors tend to be what scientists call "indolent" - so slow-growing and self-contained that many affected men die with prostate cancer, not of it. But for the percentage of men whose prostate...
View ArticleResearchers find new gene variant linked to deadly prostate cancer
Cleveland Clinic researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate cancer.
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