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Obesity linked to higher risk of prostate cancer progression

Even when treated with hormone therapy to suppress tumor growth, obese men face an elevated risk of their prostate cancer worsening, researchers at Duke University Medical Center have found.

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Antifungal drug delays need for chemo in advanced prostate cancer

The oral antifungal drug itraconazole, most commonly used to treat nail fungus, may keep prostate cancer from worsening and delay the need for chemotherapy in men with advanced disease. Details of the...

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Targeted cancer therapy kills prostate tumor cells

A new targeted therapy for prostate cancer halts tumor growth in animals with advanced prostate cancer that is resistant to hormone therapy, a new study finds. The results will be presented Saturday at...

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Rectal exams may benefit obese men more than normal-weight peers

An occasional nuisance men endure to check for prostate cancer, the digital rectal exam may have heightened importance for those who are obese.

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Researchers discover Achilles' heel in lethal form of prostate cancer

An international team of researchers led by clinicians at Weill Cornell Medical College have discovered a genetic Achilles' heel in an aggressive type of prostate cancer -- a vulnerability they say can...

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Panels recommend gearing back on prostate-cancer screenings, cancer

A blood screening result that suggests prostate cancer is bound to provoke high anxiety - even though up to 80 percent of those findings turn out to be false positives.

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Cancer treatment delivery

Humanity is on the constant search for improvements in cancer treatments, and the International Space Station has provided a microgravity platform that has enabled advancements in the cancer treatment...

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Hormone-depleting drug shows promise against localized high-risk prostate tumors

A hormone-depleting drug approved last year for the treatment of metastatic prostate cancer can help eliminate or nearly eliminate tumors in many patients with aggressive cancers that have yet to...

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'Molecular grenade': Drug from Mediterranean weed kills tumor cells in mice

Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel -- undetected by normal cells -- through the bloodstream...

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Many men with prostate cancer can avoid early surgery

(Medical Xpress) -- New research suggests that many men with prostate cancer do not need immediate treatment, especially if they have low PSA scores or low-risk tumors that are unlikely to grow and...

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Taking breaks from prostate cancer hormone therapy seems safe: study

(HealthDay)—Stop-and-start hormone-deprivation therapy for localized prostate cancer doesn't shorten overall survival compared to continuous treatments, and yields fewer side effects such as impotence...

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New research uncovers promising new biomarker for aggressiveness of prostate...

Research out of Roswell Park Cancer Institute (RPCI) supports the adoption of a new biomarker to measure the aggressiveness of primary prostate tumors. A team of investigators from three institutions,...

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COUP-TFII sparks prostate cancer progression

Prostate cancer presents a dilemma for patients and the physicians who treat them. Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and...

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Prostate cancer now detectable by imaging-guided biopsy

Ground-breaking research by a UCLA team of physicians and engineers demonstrates that prostate cancer can be diagnosed using image-guided targeted biopsy.

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FDA OKs expanded use of prostate cancer drug

(HealthDay)—The approved use of the drug Zytiga has been expanded to include treatment of men with late-stage, hormone therapy-resistant prostate cancer before they undergo chemotherapy, the U.S. Food...

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Researchers find new culprit in castration-resistant prostate cancer

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur...

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Study suggests gene variation may shape bladder cancer treatment

(Medical Xpress)—Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also...

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High fiber diet prevents prostate cancer progression

(Medical Xpress)—A high-fiber diet may have the clinical potential to control the progression of prostate cancer in patients diagnosed in early stages of the disease.

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Researchers discover protein that may control the spread of cancer

Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a...

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How some prostate tumors resist treatment—and how it might be fixed

Hormonal therapies can help control advanced prostate cancer for a time. However, for most men, at some point their prostate cancer eventually stops responding to further hormonal treatment. This stage...

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